منابع مشابه
Atopy phenotype in subjects with variants of the b subunit of the high affinity IgE receptor
b) at this chromosome 11q location and atopy by maternal descent. The identification of this Background – FceRI plays a central role in atopy, thus genetic variants of FceRI-b variant DNA has proved problematic, perhaps because of protein/DNA binding at the site, may alter receptor function to enhance atopic responses and may manifest as a but the variants we report have been confirmed by direc...
متن کاملAtopy phenotype in subjects with variants of the beta subunit of the high affinity IgE receptor.
BACKGROUND Fc epsilon RI plays a central role in atopy, thus genetic variants of Fc epsilon RI-beta may alter receptor function to enhance atopic responses and may manifest as a more severe atopic phenotype and more symptomatic atopic disease. The immunological and clinical features of atopy in children with and without the Leu 181 variant of Fc epsilon RI-beta were compared. METHODS Sixty Br...
متن کاملBeyond Atopy
The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom; Stochastic Systems Group, Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, Massachusetts; Microsoft Research Cambridge, Ca...
متن کاملAsthma and atopy
F emale sex hormones seem to have something to do with asthma and allergy. You might think this is a bit vague, but the research on this so far doesn’t merit anything stronger. Women of reproductive age are more likely to be admitted to hospital for asthma than men. Intrigued by this, people have studied the link between asthma or allergy and markers of female sex hormone levels—for example, ti...
متن کاملAtopy and Asthma
Atopy is the genetic propensity to develop an immunoglobulin E antibody response to common allergens. The most common clinical manifestations of atopy are allergic rhinitis, asthma and atopic dermatitis. Asthma is a complex disorder of the airways, involving airway hyperresponsiveness, airflow obstruction that is at least partially reversible, and inflammation of the airways. Although atopy has...
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ژورنال
عنوان ژورنال: Thorax
سال: 1998
ISSN: 0040-6376
DOI: 10.1136/thx.53.2.154a